Contact: Dr Paul Hurd Overlap: None Prerequisite: BIO163, BMD111
Prerequisites:Heredity and Gene Action (SBS008) or Chromosomes and Gene Function (SBC210). Genes occupy most of a bacterial genome, but very little of the three million kb of DNA in the 23 pairs of chromosomes in the human genome, so what is a gene? This module provides a molecular view. Gene structure is illustrated in the context of how a gene is transcribed to produce RNA, how the RNA is processed and translated to produce protein and how these processes are regulated through other DNA sequences and proteins. An introduction to bioinformatics will explain how to recognise, compile and identify genes, and infer protein sequence, from DNA sequence, including procedures for interrogating public sequence databases and phylogenetic analysis.