Dr Paul Hurd
Location: Room 4.28, Fogg building
Phone: +44 (0)20 7882 7008
The analysis and elucidation of the biological functions of epigenetic mechanisms at the cellular, whole organism and population level, using both next-generation genomics and state of the art molecular techniques.
Our major research focus concerns understanding how epigenetic mechanisms mediate interactions between the genome and environment. As illustrative examples, my lab works on three model organisms:
- Zebra finch
- Single-cell eukaryote Tetrahymena thermophilia
Epigenetics, phenotype and the environment
We use the honeybee (Apis mellifera) as a model organism to understand how nutrition interacts with the epigenome in order to orchestrate the development of three organisms from a single genome. This phenotypic polymorphism represents one of the most striking examples of developmental plasticity in any phylum.
Using the single-cell model eukaryote Tetrahymena thermophila, we are interested in the potential for epigenetic mechanisms to control how individual organisms and populations adapt to changing environmental conditions.
This work is funded by a current project grant from the BBSRC.
Epigenetics and behaviour
The songbird Taeniopygia guttata (zebra finch) is an emerging model organism for studying mechanisms of learning-and-memory. We examine the epigenetic mechanisms of gene regulation involved in long-term, experience-dependent changes in zebra finch brain function.
This work is funded by a current Principal’s PhD studentship from Queen Mary University of London.
- Browse a list of publications by Paul Hurd