Polina Reichert

Profile

Project title: Understanding the compartmentalization of glycolysis in metabolic reprogramming

Summary: Aging is associated with the loss of mitochondrial function suggesting the switch to a predominantly glycolytic lifestyle. How such an upregulation of the flux through glycolysis might occur is poorly understood. The aim of this project is to integrate genetics, biochemistry, bioinformatics and metabolomics to identify the mechanisms underlying this phenomenon and ivestigate its impact on cellular physiology. We will use yeast species with distinct approaches to aging  and metabolism as a composite model to address these questions.

Supervisor

• Dr Fabrice Caudron

Department

• Cell and Molecular Biology

Research