School of Biological and Chemical Sciences

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Josiah Seaman

PhD student



Project title: Paired Tag Markup in Eukaryotic Genomes

Summary: My goal is to develop a tool to increase detection power of all genome wide research. From my work with DNA data visualization, I discovered that the Human Genome and executable files had many of the same structural features because they both are a heterogeneous mix of blocks of code with different encodings. My hypothesis is that genomes need markers to delimit the boundaries of elements, just like how HTML comes in nested pairs of tags e.g. <div><ul></ul></div>.

If they exist, I can detect these tags statistically and use them to reverse engineer the map of all elements in any genome. This includes both known and unknown functional element boundaries, creating a new kind of annotation to aid future research.




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