Dr John Viles
Reader in Biochemistry
- Room: G.10, Joseph Priestley building
- Telephone: +44 (0)20 7882 8443
- Email: j.viles("at" sign)qmul.ac.uk
Research interests:
Research website: http://www.qmw.ac.uk/%7Eugbt002/
Role of metals in prion protein structure and function.
John Viles has an active research program studying the role of metals ions in neuro-degenerative disorders. His group uses a range of biophysical techniques, in particular nuclear magnetic resonance spectroscopy and circular dichroism, to study the factors that influence misfolding of prion protein in BSE 'mad cow' disease and the amyloid-beta-peptide in Alzheimer's disease.
Dr John H. Viles received his Ph.D. from the University of London in 1994 and continued his research with Prof P Sadler (FRS) and Prof J Thornton (OBE, FRS) studying metallo-proteins using NMR. In 1997 he took up a post-doctoral position with Prof P Wright at the Scripps Research Institute, California. In collaboration with the Nobel Laureate, Prof S Prusiner, he has published a number of significant papers on structure and function of the prion protein. Prions are the novel infectious agent of BSE and CJD in humans. He returned to the UK in 2000 to take up a lectureship position at Queen Mary and is currently a senior lecturer in biochemistry at Queen Mary, University of London.
Research group:
Postgraduate supervision:
Stanyon, Helen; h.f.stanyon ("at" sign) qmul.ac.uk;
Wright, Hannah; h.wright ("at" sign) qmul.ac.uk;
Younan, Nadine; n.younan ("at" sign) qmul.ac.uk;