Dr David Pritchett
Postdoctoral Research Assistant
Email: email@example.comTelephone: +44 (0)20 7882 6106Room Number: 2.26, Fogg building
I have a longstanding interest in the neurobiological basis of cognition. During my PhD, I worked with a number of schizophrenia-relevant transgenic mouse models, using a variety of behavioural assays to assess their memory performance. Here at Queen Mary University of London, I am using transgenic zebrafish to investigate the neurobiological basis of number cognition. More specifically, I am testing the hypothesis that the ability to represent number is genetically regulated and has an evolutionarily conserved basis. My research aims are as follows:
(1) to develop an automated behavioural assay to assess the numerical ability of zebrafish;
(2) to characterise the numerical ability of adult wildtype zebrafish;
(3) to identify genetic variants that influence adult zebrafish performance; and
(4) to establish whether there is overlap in the genetic loci that affect zebrafish and human number cognition.
If there is significant overlap, then zebrafish could be used as a model organism to study the neural circuitry that underlies number processing, which one day could lead to the development of treatments for dyscalculia (a specific learning difficulty for mathematics). My work will involve the use of automated behavioural testing chambers, developed by Zantiks. My project is funded by the Leverhulme Trust.