Evolutionary and organismal biology
The Evolutionary and Organismal Biology Group (EOBG) is internationally recognised for using post-genomic approaches to investigate the evolution and functions of genes and proteins at an organismal level using a range of model organisms, including plants, invertebrates, fish and mammals. An underlying theme is a recognition of the importance of comparative and functional genomics in modern systems biology. It encompasses research on chromosome evolution in plants, transposable elements in insects, functional genomics and developmental biology (using Danio rerio and Fugu rubripes as vertebrate model systems), molecular neurobiology (eg endocannabinoid signalling), behavioural genetics (eg circadian biology of Drosophila) and population genetics of humans and other animals. This research utilises a range of methods including bioinformatics, analysis of cell and tissue structure, analysis of gene and protein expression and the impact of gene-knockout on phenotypes, in vitro physiology and pharmacology and analysis of whole-organism behaviour.
Members
- Rachel Ashworth
- Caroline Brennan
- Richard Buggs
- Brendan Curran
- Maurice Elphick
- Paul Hurd
- Steve Le Comber
- Andrew Leitch
- Colin Malcolm
- Fanis Missirlis
- Richard Nichols
- Ian Phillips
- John Puddefoot
- Steve Rossiter
- Peter Skorupski
- Ralf Stanewsky
- Angelika Stollewerk
- Matthew Struebig
- Yannick Wurm
Please see the group members' individual web pages for recent publications and research interests.