Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)

Enzyme Nomenclature

Supplement 24 (2018)

The following documents with additions and amendments to Enzyme Nomenclature have been approved after public review:

New enzymes (20 February 2018, approved 19 March 2018)
New enzymes (29 March 2018, approved 29 March 2018)
New enzymes (21 May 2018, approved 21 May 2018)
New enzymes (28 June 2018, approved 26 July 2018)
New enzymes (29 August 2018, approved 21 September2018)
The entries were added on the date indicated and fully approved after a month. An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry.


Contents

*EC 1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase (21 May 2018)
EC 1.1.1.314 deleted, now known to be catalyzed by EC 1.14.14.95 (29 August 2018)
EC 1.1.1.414 L-galactonate 5-dehydrogenase (29 August 2018)
*EC 1.1.3.2 L-lactate oxidase (29 March 2018)
EC 1.1.99.42 4-pyridoxic acid dehydrogenase (21 May 2018)
EC 1.2.1.100 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase (21 May 2018)
EC 1.3.1.114 3-dehydro-bile acid Δ4,6-reductase (21 May 2018)
EC 1.3.1.115 3-oxocholoyl-CoA 4-desaturase (21 May 2018)
EC 1.3.1.116 7β-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase (21 May 2018)
EC 1.3.1.117 hydroxycinnamoyl-CoA reductase (21 May 2018)
EC 1.3.3.9 transferred now EC 1.14.19.62 (26 July 2018)
EC 1.3.99.39 carotenoid φ-ring synthase (21 May 2018)
EC 1.3.99.40 carotenoid χ-ring synthase (21 May 2018)
EC 1.6.1.5 transferred, now EC 7.1.1.1 (29 August 2018)
EC 1.6.5.3 transferred, now EC 7.1.1.2 (29 August 2018)
EC 1.6.5.8 transferred, now EC 7.2.1.1 (29 August 2018)
EC 1.7.1.17 FMN-dependent NADH-azoreductase (29 March 2018)
EC 1.8.2.6 S-disulfanyl-L-cysteine oxidoreductase (20 February 2018)
EC 1.13.11.85 exo-cleaving rubber dioxygenase (29 March 2018)
EC 1.13.11.86 5-aminosalicylate 1,2-dioxygenase (29 August 2018)
EC 1.13.12.24 calcium-regulated photoprotein (20 February 2018)
EC 1.14.11.14 transferred now EC 1.14.20.13 (21 May 2018)
EC 1.14.11.19 transferred now EC 1.14.20.4 (29 March 2018)
EC 1.14.11.22 transferred now EC 1.14.20.5 (29 March 2018)
EC 1.14.11.23 transferred now EC 1.14.20.6 (29 March 2018)
EC 1.14.11.34 transferred now EC 1.14.20.7 (29 March 2018)
EC 1.14.11.50 transferred now EC 1.14.20.8 (29 March 2018)
EC 1.14.11.58 ornithine lipid ester-linked acyl 2-hydroxylase (20 February 2018)
EC 1.14.11.59 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase (20 February 2018)
EC 1.14.12.4 transferred now EC 1.14.13.242 (21 May 2018)
EC 1.14.12.5 transferred now EC 1.14.13.241 (21 May 2018)
EC 1.14.13.11 transferred now EC 1.14.14.91 (26 July 2018)
EC 1.14.13.12 transferred now EC 1.14.14.92 (26 July 2018)
EC 1.14.13.21 transferred now EC 1.14.14.82 (21 May 2018)
EC 1.14.13.28 transferred now EC 1.14.14.93 (26 July 2018)
EC 1.14.13.30 transferred now EC 1.14.14.94 (26 July 2018)
*EC 1.14.13.32 albendazole monooxygenase (flavin-containing) (21 May 2018)
EC 1.14.13.36 transferred now EC 1.14.14.96 (26 July 2018)
EC 1.14.13.37 transferred now EC 1.14.14.97 (26 July 2018)
EC 1.14.13.47 transferred now EC 1.14.14.99 (26 July 2018)
EC 1.14.13.52 transferred now EC 1.14.14.88 (26 July 2018)
EC 1.14.13.53 transferred now EC 1.14.14.89 (26 July 2018)
EC 1.14.13.55 transferred now EC 1.14.14.98 (26 July 2018)
EC 1.14.13.56 transferred now EC 1.14.14.100 (26 July 2018)
EC 1.14.13.57 transferred now EC 1.14.14.101 (26 July 2018)
EC 1.14.13.70 transferred now EC 1.14.14.154 (26 July 2018)
EC 1.14.13.71 transferred now EC 1.14.14.102 (26 July 2018)
EC 1.14.13.73 transferred now EC 1.14.14.103 (26 July 2018)
EC 1.14.13.74 transferred now EC 1.14.14.85 (21 May 2018)
EC 1.14.13.75 transferred now EC 1.14.14.104 (26 July 2018)
EC 1.14.13.76 transferred now EC 1.14.14.105 (26 July 2018)
EC 1.14.13.77 transferred now EC 1.14.14.106 (26 July 2018)
EC 1.14.13.78 transferred now EC 1.14.14.86 (21 May 2018)
EC 1.14.13.79 transferred now EC 1.14.14.107 (26 July 2018)
EC 1.14.13.85 transferred now EC 1.14.14.135 (26 July 2018)
EC 1.14.13.87 transferred now EC 1.14.14.140 (26 July 2018)
EC 1.14.13.88 transferred now EC 1.14.14.81 (21 May 2018)
EC 1.14.13.89 transferred now EC 1.14.14.90 (26 July 2018)
EC 1.14.13.97 transferred now EC 1.14.14.57 (20 February 2018)
EC 1.14.13.91 transferred now EC 1.14.14.136 (26 July 2018)
EC 1.14.13.93 transferred now EC 1.14.14.137 (26 July 2018)
EC 1.14.13.94 transferred now EC 1.14.14.138 (26 July 2018)
EC 1.14.13.96 transferred now EC 1.14.14.139 (26 July 2018)
EC 1.14.13.102 transferred now EC 1.14.14.141 (26 July 2018)
EC 1.14.13.103 transferred now EC 1.14.14.142 (26 July 2018)
EC 1.14.13.104 transferred now EC 1.14.14.143 (26 July 2018)
EC 1.14.13.108 transferred now EC 1.14.14.144 (26 July 2018)
EC 1.14.13.109 transferred now EC 1.14.14.145 (26 July 2018)
EC 1.14.13.110 transferred now EC 1.14.14.146 (26 July 2018)
EC 1.14.13.112 transferred now EC 1.14.14.147 (26 July 2018)
EC 1.14.13.115 transferred now EC 1.14.14.148 (26 July 2018)
EC 1.14.13.119 transferred now EC 1.14.14.149 (26 July 2018)
EC 1.14.13.120 transferred now EC 1.14.14.150 (26 July 2018)
EC 1.14.13.121 transferred now EC 1.14.14.151 (26 July 2018)
EC 1.14.13.123 transferred now EC 1.14.14.95 (26 July 2018)
EC 1.14.13.125 >transferred, now EC 1.14.14.156 (29 August 2018)
EC 1.14.13.133 transferred now EC 1.14.15.32 (26 July 2018)
EC 1.14.13.134 transferred now EC 1.14.14.152 (26 July 2018)
EC 1.14.13.136 transferred now EC 1.14.14.87 (21 May 2018)
EC 1.14.13.137 transferred now EC 1.14.14.153 (26 July 2018)
EC 1.14.13.138 transferred, now EC 1.14.14.157 (29 August 2018)
EC 1.14.13.139 transferred now EC 1.14.14.109 (26 July 2018)
EC 1.14.13.140 transferred now EC 1.14.14.110 (26 July 2018)
EC 1.14.13.141 transferred now EC 1.14.15.29 (21 May 2018)
EC 1.14.13.142 transferred now EC 1.14.15.30 (26 July 2018)
EC 1.14.13.143 transferred now EC 1.14.14.76 (21 May 2018)
EC 1.14.13.144 transferred now EC 1.14.14.111 (26 July 2018)
EC 1.14.13.145 transferred now EC 1.14.14.112 (26 July 2018)
EC 1.14.13.150 transferred now EC 1.14.14.113 (26 July 2018)
EC 1.14.13.151 transferred now EC 1.14.14.84 (21 May 2018)
EC 1.14.13.152 transferred now EC 1.14.14.83 (21 May 2018)
EC 1.14.13.156 transferred now EC 1.14.14.133 (26 July 2018)
EC 1.14.13.158 transferred now EC 1.14.14.114 (26 July 2018)
EC 1.14.13.162 transferred now EC 1.14.14.108 (26 July 2018)
EC 1.14.13.173 transferred now EC 1.14.14.115 (26 July 2018)
EC 1.14.13.174 transferred now EC 1.14.14.116 (26 July 2018)
EC 1.14.13.175 transferred now EC 1.14.14.117 (26 July 2018)
EC 1.14.13.176 transferred now EC 1.14.14.118 (26 July 2018)
EC 1.14.13.177 transferred now EC 1.14.14.119 (26 July 2018)
EC 1.14.13.183 transferred now EC 1.14.14.120 (26 July 2018)
EC 1.14.13.184 transferred now EC 1.14.14.121 (26 July 2018)
EC 1.14.13.185 transferred now EC 1.14.15.33 (26 July 2018)
EC 1.14.13.186 transferred now EC 1.14.15.34 (26 July 2018)
EC 1.14.13.188 transferred now EC 1.14.15.35 (26 July 2018)
EC 1.14.13.191 transferred now EC 1.14.14.70 (29 March 2018)
EC 1.14.13.192 transferred now EC 1.14.14.122 (26 July 2018)
EC 1.14.13.193 transferred now EC 1.14.14.123 (26 July 2018)
EC 1.14.13.194 transferred now EC 1.14.14.78 (21 May 2018)
EC 1.14.13.197 transferred now EC 1.14.14.124 (26 July 2018)
EC 1.14.13.198 transferred now EC 1.14.14.125 (26 July 2018)
EC 1.14.13.199 transferred now EC 1.14.14.79 (21 May 2018)
EC 1.14.13.201 transferred now EC 1.14.14.126 (26 July 2018)
EC 1.14.13.202 transferred now EC 1.14.14.127 (26 July 2018)
EC 1.14.13.203 transferred now EC 1.14.14.128 (26 July 2018)
EC 1.14.13.204 transferred now EC 1.14.14.129 (26 July 2018)
EC 1.14.13.205 transferred now EC 1.14.14.80 (21 May 2018)
EC 1.14.13.206 transferred now EC 1.14.14.130 (26 July 2018)
EC 1.14.13.213 transferred now EC 1.14.14.131 (26 July 2018)
EC 1.14.13.214 transferred now EC 1.14.14.132 (26 July 2018)
EC 1.14.13.221 transferred now EC 1.14.15.28 (21 May 2018)
EC 1.14.13.240 2-polyprenylphenol 6-hydroxylase (21 May 2018)
EC 1.14.13.241 5-pyridoxate monooxygenase (21 May 2018)
EC 1.14.13.242 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase (21 May 2018)
*EC 1.14.14.56 1,8-cineole 2-exo-monooxygenase (21 May 2018)
EC 1.14.14.57 taurochenodeoxycholate 6α-hydroxylase (20 February 2018)
EC 1.14.14.58 trimethyltridecatetraene synthase (20 February 2018)
EC 1.14.14.59 dimethylnonatriene synthase (20 February 2018)
EC 1.14.14.60 ferruginol monooxygenase (20 February 2018)
EC 1.14.14.61 carnosic acid synthase (20 February 2018)
EC 1.14.14.62 salviol synthase (20 February 2018)
EC 1.14.14.63 β-amyrin 16β-monooxygenase (20 February 2018)
EC 1.14.14.64 β-amyrin 6β-monooxygenase (20 February 2018)
EC 1.14.14.65 sugiol synthase (20 February 2018)
EC 1.14.14.66 marmesin synthase (20 February 2018)
EC 1.14.14.67 11-hydroxysugiol 20-monooxygenase (20 February 2018)
EC 1.14.14.68 syn-pimaradiene 3-monooxygenase (20 February 2018)
EC 1.14.14.69 ent-cassadiene hydroxylase (20 February 2018)
EC 1.14.14.70 ent-sandaracopimaradiene 3-hydroxylase (29 March 2018)
EC 1.14.14.71 cucurbitadienol 11-hydroxylase (29 March 2018)
EC 1.14.14.72 drimenol monooxygenase (29 March 2018)
EC 1.14.14.73 albendazole monooxygenase (sulfoxide-forming) (21 May 2018)
EC 1.14.14.74 albendazole monooxygenase (hydroxylating) (21 May 2018)
EC 1.14.14.75 fenbendazole monooxygenase (4'-hydroxylating) (21 May 2018)
EC 1.14.14.76 ent-isokaurene C2/C3-hydroxylase (21 May 2018)
EC 1.14.14.77 phenylacetonitrile α-monooxygenase (21 May 2018)
EC 1.14.14.78 phylloquinone ω-hydroxylase (21 May 2018)
EC 1.14.14.79 docosahexaenoic acid ω-hydroxylase (21 May 2018)
EC 1.14.14.80 long-chain fatty acid ω-monooxygenase (21 May 2018)
EC 1.14.14.81 flavanoid 3',5'-hydroxylase (21 May 2018)
EC 1.14.14.82 flavonoid 3'-monooxygenase (21 May 2018)
EC 1.14.14.83 geraniol 8-hydroxylase (21 May 2018)
EC 1.14.14.84 linalool 8-monooxygenase (21 May 2018)
EC 1.14.14.85 7-deoxyloganin 7-hydroxylase (21 May 2018)
EC 1.14.14.86 ent-kaurene monooxygenase (21 May 2018)
EC 1.14.14.87 2-hydroxyisoflavanone synthase (21 May 2018)
EC 1.14.14.88 isoflavone 3'-hydroxylase (26 July 2018)
EC 1.14.14.89 4'-methoxyisoflavone 2'-hydroxylase (26 July 2018)
EC 1.14.14.90 isoflavone 2'-hydroxylase (26 July 2018)
EC 1.14.14.91 trans-cinnamate 4-monooxygenase (26 July 2018)
EC 1.14.14.92 benzoate 4-monooxygenase (26 July 2018)
EC 1.14.14.93 3,9-dihydroxypterocarpan 6a-monooxygenase (26 July 2018)
EC 1.14.14.94 leukotriene-B4 20-monooxygenase (26 July 2018)
EC 1.14.14.95 germacrene A hydroxylase (26 July 2018)
EC 1.14.14.96 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase (26 July 2018)
EC 1.14.14.97 methyltetrahydroprotoberberine 14-monooxygenase (26 July 2018)
EC 1.14.14.98 protopine 6-monooxygenase (26 July 2018)
EC 1.14.14.99 (S)-limonene 3-monooxygenase (26 July 2018)
EC 1.14.14.100 dihydrosanguinarine 10-monooxygenase (26 July 2018)
EC 1.14.14.101 dihydrochelirubine 12-monooxygenase (26 July 2018)
EC 1.14.14.102 N-methylcoclaurine 3'-monooxygenase (26 July 2018)
EC 1.14.14.103 tabersonine 16-hydroxylase (26 July 2018)
EC 1.14.14.104 vinorine hydroxylase (26 July 2018)
EC 1.14.14.105 taxane 10β-hydroxylase (26 July 2018)
EC 1.14.14.106 taxane 13α-hydroxylase (26 July 2018)
EC 1.14.14.107 ent-kaurenoic acid monooxygenase (26 July 2018)
EC 1.14.14.108 2,5-diketocamphane 1,2-monooxygenase (26 July 2018)
EC 1.14.14.109 3-hydroxyindolin-2-one monooxygenase (26 July 2018)
EC 1.14.14.110 2-hydroxy-1,4-benzoxazin-3-one monooxygenase (26 July 2018)
EC 1.14.14.111 9β-pimara-7,15-diene oxidase (26 July 2018)
EC 1.14.14.112 ent-cassa-12,15-diene 11-hydroxylase (26 July 2018)
EC 1.14.14.113 α-humulene 10-hydroxylase (26 July 2018)
EC 1.14.14.114 amorpha-4,11-diene 12-monooxygenase (26 July 2018)
EC 1.14.14.115 11-oxo-β-amyrin 30-oxidase (26 July 2018)
EC 1.14.14.116 averantin hydroxylase (26 July 2018)
EC 1.14.14.117 aflatoxin B synthase (26 July 2018)
EC 1.14.14.118 tryprostatin B 6-hydroxylase (26 July 2018)
EC 1.14.14.119 fumitremorgin C monooxygenase (26 July 2018)
EC 1.14.14.120 dammarenediol 12-hydroxylase (26 July 2018)
EC 1.14.14.121 protopanaxadiol 6-hydroxylase (26 July 2018)
EC 1.14.14.122 oryzalexin E synthase (26 July 2018)
EC 1.14.14.123 oryzalexin D synthase (26 July 2018)
EC 1.14.14.124 dihydromonacolin L hydroxylase (26 July 2018)
EC 1.14.14.125 monacolin L hydroxylase (26 July 2018)
EC 1.14.14.126 β-amyrin 28-monooxygenase (26 July 2018)
EC 1.14.14.127 methyl farnesoate epoxidase (26 July 2018)
EC 1.14.14.128 farnesoate epoxidase (26 July 2018)
EC 1.14.14.129 long-chain acyl-CoA ω-monooxygenase (26 July 2018)
EC 1.14.14.130 laurate 7-monooxygenase (26 July 2018)
EC 1.14.14.131 bursehernin 5'-monooxygenase (26 July 2018)
EC 1.14.14.132 (–)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase (26 July 2018)
EC 1.14.14.133 1,8-cineole 2-endo-monooxygenase (26 July 2018)
EC 1.14.14.134 β-amyrin 24-hydroxylase (26 July 2018)
EC 1.14.14.135 glyceollin synthase (26 July 2018)
EC 1.14.14.136 deoxysarpagine hydroxylase (26 July 2018)
EC 1.14.14.137 (+)-abscisic acid 8'-hydroxylase (26 July 2018)
EC 1.14.14.138 lithocholate 6β-hydroxylase (26 July 2018)
EC 1.14.14.139 5β-cholestane-3α,7α-diol 12α-hydroxylase (26 July 2018)
EC 1.14.14.140 licodione synthase (26 July 2018)
EC 1.14.14.141 psoralen synthase (26 July 2018)
EC 1.14.14.142 8-dimethylallylnaringenin 2'-hydroxylase (26 July 2018)
EC 1.14.14.143 (+)-menthofuran synthase (26 July 2018)
EC 1.14.14.144 abieta-7,13-diene hydroxylase (26 July 2018)
EC 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase (26 July 2018)
EC 1.14.14.146 geranylgeraniol 18-hydroxylase (26 July 2018)
EC 1.14.14.147 3-epi-6-deoxocathasterone 23-monooxygenase (26 July 2018)
EC 1.14.14.148 angelicin synthase (26 July 2018)
EC 1.14.14.149 5-epiaristolochene 1,3-dihydroxylase (26 July 2018)
EC 1.14.14.150 costunolide synthase (26 July 2018)
EC 1.14.14.151 premnaspirodiene oxygenase (26 July 2018)
EC 1.14.14.152 β-amyrin 11-oxidase (26 July 2018)
EC 1.14.14.153 indole-2-monooxygenase (26 July 2018)
EC 1.14.14.154 sterol 14α-demethylase (26 July 2018)
EC 1.14.14.155 3,6-diketocamphane 1,2-monooxygenase (29 August 2018)
EC 1.14.14.156 tryptophan N-monooxygenase (29 August 2018)
EC 1.14.14.157 indolin-2-one monooxygenase (29 August 2018)
EC 1.14.14.158 carotenoid ε hydroxylase (29 August 2018)
EC 1.14.15.25 p-cymene methyl-monooxygenase (20 February 2018)
EC 1.14.15.26 toluene methyl-monooxygenase (20 February 2018)
EC 1.14.15.27 β-dihydromenaquinone-9 ω-hydroxylase (21 May 2018)
EC 1.14.15.28 cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] (21 May 2018)
EC 1.14.15.29 cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming] (21 May 2018)
EC 1.14.15.30 3-ketosteroid 9α-monooxygenase (21 May 2018)
EC 1.14.15.31 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase (26 July 2018)
EC 1.14.15.32 pentalenene oxygenase (26 July 2018)
EC 1.14.15.33 pikromycin synthase (26 July 2018)
EC 1.14.15.34 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase (26 July 2018)
EC 1.14.15.35 6-deoxyerythronolide B hydroxylase (26 July 2018)
*EC 1.14.19.9 tryptophan 7-halogenase (29 March 2018)
EC 1.14.19.53 all-trans-retinol 3,4-desaturase (20 February 2018)
EC 1.14.19.54 1,2-dehydroreticuline synthase (29 March 2018)
EC 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating) (29 March 2018)
EC 1.14.19.56 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase (29 March 2018)
EC 1.14.19.57 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase (29 March 2018)
EC 1.14.19.58 tryptophan 5-halogenase (29 March 2018)
EC 1.14.19.59 tryptophan 6-halogenase (29 March 2018)
EC 1.14.19.60 7-chloro-L-tryptophan 6-halogenase (29 March 2018)
EC 1.14.19.61 dihydrorhizobitoxine desaturase (21 May 2018)
EC 1.14.19.62 secologanin synthase (26 July 2018)
EC 1.14.19.63 pseudobaptigenin synthase (26 July 2018)
EC 1.14.19.64 (S)-stylopine synthase (26 July 2018)
EC 1.14.19.65 (S)-cheilanthifoline synthase (26 July 2018)
EC 1.14.19.66 berbamunine synthase (26 July 2018)
EC 1.14.19.67 salutaridine synthase (26 July 2018)
EC 1.14.19.68 (S)-canadine synthase (26 July 2018)
EC 1.14.19.69 biflaviolin synthase (26 July 2018)
EC 1.14.19.70 mycocyclosin synthase (26 July 2018)
EC 1.14.19.71 fumitremorgin C synthase (26 July 2018)
EC 1.14.19.72 (–)-pluviatolide synthase (26 July 2018)
EC 1.14.19.73 (S)-nandinine synthase (26 July 2018)
EC 1.14.19.74 (+)-piperitol/(+)-sesamin synthase (29 August 2018)
EC 1.14.20.2 transferred now EC 1.14.11.59 (20 February 2018)
EC 1.14.20.4 anthocyanidin synthase (29 March 2018)
EC 1.14.20.5 flavone synthase I (29 March 2018)
EC 1.14.20.6 flavonol synthase (29 March 2018)
EC 1.14.20.7 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) (29 March 2018)
EC 1.14.20.8 (–)-deoxypodophyllotoxin synthase (29 March 2018)
EC 1.14.20.9 L-tyrosine isonitrile desaturase (21 May 2018)
EC 1.14.20.10 L-tyrosine isonitrile desaturase/decarboxylase (21 May 2018)
EC 1.14.20.11 3-[(Z)-2-isocyanoethenyl]-1H-indole synthase (21 May 2018)
EC 1.14.20.12 3-[(E)-2-isocyanoethenyl]-1H-indole synthase (21 May 2018)
EC 1.14.20.13 6β-hydroxyhyoscyamine epoxidase (21 May 2018)
EC 1.14.20.14 hapalindole-type alkaloid chlorinase (29 August 2018)
EC 1.14.20.15 L-threonyl-[L-threonyl-carrier protein] 4-chlorinase (29 August 2018)
EC 1.14.21.1 transferred now EC 1.14.19.64 (26 July 2018)
EC 1.14.21.2 transferred now EC 1.14.19.65 (26 July 2018)
EC 1.14.21.3 transferred now EC 1.14.19.66 (26 July 2018)
EC 1.14.21.4 transferred now EC 1.14.19.67 (26 July 2018)
EC 1.14.21.5 transferred now EC 1.14.19.68 (26 July 2018)
EC 1.14.21.7 transferred now EC 1.14.19.69 (26 July 2018)
EC 1.14.21.8 transferred now EC 1.14.19.63 (26 July 2018)
EC 1.14.21.9 transferred now EC 1.14.19.70 (26 July 2018)
EC 1.14.21.10 transferred now EC 1.14.19.71 (26 July 2018)
EC 1.14.21.11 transferred now EC 1.14.19.72 (26 July 2018)
EC 1.14.21.12 transferred now EC 1.14.19.73 (26 July 2018)
EC 1.14.99.43 transferred now EC 1.14.14.134 (26 July 2018)
EC 1.14.99.45 transferred, now EC 1.14.14.158 (29 August 2018)
EC 1.14.99.49 transferred now EC 1.14.15.31 (26 July 2018)
EC 1.14.99.60 3-demethoxyubiquinol 3-hydroxylase (21 May 2018)
EC 1.14.99.61 cyclooctat-9-en-7-ol 5-monooxygenase (29 August 2018)
EC 1.14.99.62 cyclooctatin synthase (29 August 2018)
EC 1.14.99.63 β-carotene 4-ketolase (29 August 2018)
EC 1.14.99.64 zeaxanthin 4-ketolase (29 August 2018)
EC 1.17.9 With a copper protein as acceptor (26 July 2018)
EC 1.17.9.1 4-methylphenol dehydrogenase (hydroxylating) (26 July 2018)
EC 1.17.99.1 transferred now EC 1.17.9.71 (26 July 2018)
EC 1.18.1.8 transferred, now EC 7.2.1.2 (29 August 2018)
*EC 1.18.6.1 nitrogenase (21 May 2018)
EC 1.18.6.2 vanadium-dependent nitrogenase (21 May 2018)
EC 1.21.98.4 PqqA peptide cyclase (29 August 2018)
*EC 2.1.1.294 3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase (20 February 2018)
EC 2.1.1.346 U6 snRNA m6A methyltransferase (20 February 2018)
EC 2.1.1.347 (+)-O-methylkolavelool synthase (20 February 2018)
EC 2.1.1.348 mRNA m6A methyltransferase (29 March 2018)
EC 2.1.1.349 toxoflavin synthase (29 August 2018)
EC 2.1.5 Methylenetransferases (20 February 2018)
EC 2.1.5.1 sesamin methylene transferase (20 February 2018)
*EC 2.3.1.74 chalcone synthase (21 May 2018)
EC 2.3.1.96 deleted (20 February 2018)
*EC 2.3.1.97 glycylpeptide N-tetradecanoyltransferase (21 May 2018)
EC 2.3.1.128 transferred now EC 2.3.1.266 and EC 2.3.1.267(20 February 2018)
EC 2.3.1.266 [ribosomal protein S18]-alanine N-acetyltransferase (20 February 2018)
EC 2.3.1.267 [ribosomal protein S5]-alanine N-acetyltransferase (20 February 2018)
EC 2.3.1.268 ethanol O-acetyltransferase (20 February 2018)
EC 2.3.1.269 apolipoprotein N-acyltransferase (21 May 2018)
EC 2.3.1.270 lyso-ornithine lipid O-acyltransferase (21 May 2018)
EC 2.3.1.271 L-glutamate-5-semialdehyde N-acetyltransferase (21 May 2018)
EC 2.3.1.272 2-acetylphloroglucinol acetyltransferase (21 May 2018)
EC 2.3.1.273 diglucosylglycerate octanoyltransferase (29 August 2018)
EC 2.3.3.20 acyl-CoA:acyl-CoA alkyltransferase (20 February 2018)
*EC 2.4.1.53 poly(ribitol-phosphate) β-glucosyltransferase (29 March 2018)
*EC 2.4.1.70 poly(ribitol-phosphate) α-N-acetylglucosaminyltransferase (29 March 2018)
EC 2.4.1.95 deleted (21 May 2018)
*EC 2.4.1.101 α-1,3-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase (29 March 2018)
*EC 2.4.1.102 β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase (21 May 2018)
*EC 2.4.1.143 α-1,6-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase (29 March 2018)
*EC 2.4.1.144 β-1,4-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase (29 March 2018)
*EC 2.4.1.145 α-1,3-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase (29 March 2018)
*EC 2.4.1.146 β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase (21 May 2018)
*EC 2.4.1.155 α-1,6-mannosyl-glycoprotein 6-β-N-acetylglucosaminyltransferase (21 May 2018)
*EC 2.4.1.195 N-hydroxythioamide S-β-glucosyltransferase (29 March 2018)
*EC 2.4.1.201 α-1,6-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase (29 March 2018)
*EC 2.4.1.226 N-acetylgalactosaminyl-proteoglycan 3-β-glucuronosyltransferase (21 May 2018)
EC 2.4.1.351 rhamnogalacturonan I rhamnosyltransferase (20 February 2018)
EC 2.4.1.352 glucosylglycerate phosphorylase (20 February 2018)
EC 2.4.1.353 sordaricin 6-deoxyaltrosyltransferase (29 March 2018)
EC 2.4.1.354 (R)-mandelonitrile β-glucosyltransferase (29 March 2018)
EC 2.4.1.355 poly(ribitol-phosphate) β-N-acetylglucosaminyltransferase (29 March 2018)
EC 2.4.1.356 glucosyl-dolichyl phosphate glucuronosyltransferase (21 May 2018)
EC 2.4.1.357 phlorizin synthase (21 May 2018)
EC 2.4.1.358 acylphloroglucinol glucosyltransferase (29 August 2018)
EC 2.4.2.59 sulfide-dependent adenosine diphosphate thiazole synthase (29 March 2018)
EC 2.4.2.60 cysteine-dependent adenosine diphosphate thiazole synthase (29 March 2018)
*EC 2.5.1.17 corrinoid adenosyltransferase (29 August 2018)
EC 2.5.1.77 transferred, now EC 2.5.1.147 and EC 4.3.1.32 (29 August 2018)
*EC 2.5.1.98 Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase (20 February 2018)
EC 2.5.1.99 deleted (20 February 2018)
EC 2.5.1.143 pyridinium-3,5-biscarboxylic acid mononucleotide synthase (29 March 2018)
EC 2.5.1.144 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) (21 May 2018)
EC 2.5.1.145 phosphatidylglycerol—prolipoprotein diacylglyceryl transferase (21 May 2018)
EC 2.5.1.146 3-geranyl-3-[(Z)-2-isocyanoethenyl]indole synthase (21 May 2018)
EC 2.5.1.147 5-amino-6-(D-ribitylamino)uracil—L-tyrosine 4-hydroxyphenyl transferase (29 August 2018)
*EC 2.6.1.92 UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine transaminase (21 May 2018)
EC 2.6.1.114 8-demethyl-8-aminoriboflavin-5′-phosphate synthase (20 February 2018)
*EC 2.7.1.209 L-erythrulose 1-kinase (29 March 2018)
*EC 2.7.2.2 carbamate kinase (29 August 2018)
EC 2.7.7.100 SAMP-activating enzyme (21 May 2018)
EC 2.7.9.6 rifampicin phosphotransferase (20 February 2018)
*EC 2.8.1.2 3-mercaptopyruvate sulfurtransferase (20 February 2018)
*EC 2.8.1.8 lipoyl synthase (29 March 2018)
EC 2.8.5 Thiosulfotransferases (21 May 2018)
EC 2.8.5.1 S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent) (21 May 2018)
EC 2.8.5.2 L-cysteine S-thiosulfotransferase (29 August 2018)
EC 3.1.1.103 teichoic acid D-alanine hydrolase (20 February 2018)
EC 3.1.6.20 S-sulfosulfanyl-L-cysteine sulfohydrolase (21 May 2018)
*EC 3.2.1.106 mannosyl-oligosaccharide glucosidase (29 March 2018)
*EC 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-α-mannosidase (29 March 2018)
*EC 3.2.1.170 mannosylglycerate hydrolase (21 May 2018)
EC 3.2.1.207 mannosyl-oligosaccharide α-1,3-glucosidase (29 March 2018)
EC 3.2.2.31 adenine glycosylase (20 February 2018)
*EC 3.3.1.2 S-adenosyl-L-methionine hydrolase (L-homoserine-forming) (21 May 2018)
*EC 3.4.19.9 folate γ-glutamyl hydrolase (29 August 2018)
EC 3.5.1.128 deaminated glutathione amidase (29 March 2018)
EC 3.6.3.1 transferred, now EC 7.6.2.1 (29 August 2018)
EC 3.6.3.6 transferred, now EC 7.1.2.1 (29 August 2018)
EC 3.6.3.7 transferred, now EC 7.2.2.3 (29 August 2018)
EC 3.6.3.14 transferred, now EC 7.1.2.2 (29 August 2018)
EC 3.6.3.15 transferred, now EC 7.2.2.1 (29 August 2018)
EC 3.6.3.18 transferred, now EC 7.5.2.2 (29 August 2018)
EC 3.6.3.19 transferred, now EC 7.5.2.1 (29 August 2018)
EC 3.6.3.21 transferred, now EC 7.4.2.1 (29 August 2018)
EC 3.6.3.22 transferred, now EC 7.4.2.2 (29 August 2018)
EC 3.6.3.27 transferred, now EC 7.3.2.1 (29 August 2018)
EC 3.6.3.28 transferred, now EC 7.3.2.2 (29 August 2018)
EC 3.6.3.44 transferred, now EC 7.6.2.2 (29 August 2018)
EC 3.6.3.46 transferred, now EC 7.2.2.2 (29 August 2018)
EC 3.6.4.3 transferred, now EC 5.6.1.1 (29 August 2018)
EC 3.6.4.11 deleted (29 August 2018)
*EC 3.7.1.4 phloretin hydrolase (29 March 2018)
EC 3.13.1.7 carbonyl sulfide hydrolase (20 February 2018)
EC 3.13.1.8 S-adenosyl-L-methionine hydrolase (adenosine-forming) (21 May 2018)
EC 4.1.1.3 transferred, now EC 7.2.4.2 and EC 4.1.1.112 (29 August 2018)
EC 4.1.1.41 transferred, now EC 7.2.4.3 (29 August 2018)
*EC 4.1.1.99 phosphomevalonate decarboxylase (29 August 2018)
EC 4.1.1.110 bisphosphomevalonate decarboxylase (21 May 2018)
EC 4.1.1.111 siroheme decarboxylase (21 May 2018)
EC 4.1.1.112 oxaloacetate decarboxylase (29 August 2018)
EC 4.1.99.24 L-tyrosine isonitrile synthase (29 August 2018)
EC 4.1.99.25 L-tryptophan isonitrile synthase (29 August 2018)
EC 4.3.1.32 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase (29 August 2018)
EC 4.3.2.10 imidazole glycerol-phosphate synthase (29 August 2018)
EC 4.3.99.2 transferred, now EC 7.2.4.1 (29 August 2018)
EC 4.4.1.6 transferred, now included in EC 4.4.1.13 (29 August 2018)
EC 4.4.1.8 transferred, now included in EC 4.4.1.13 (29 August 2018)
EC 4.4.1.37 pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase (21 May 2018)
EC 5.1.3.39 deleted (20 February 2018)
*EC 5.3.3.8 Δ32-enoyl-CoA isomerase (20 February 2018)
EC 5.3.3.21 Δ3,52,4-dienoyl-CoA isomerase (20 February 2018)
EC 5.3.3.22 lutein isomerase (29 March 2018)
EC 5.5.1.31 hapalindole H synthase (29 March 2018)
EC 5.5.1.32 12-epi-hapalindole U synthase (29 March 2018)
EC 5.5.1.33 12-epi-fischerindole U synthase (29 March 2018)
EC 5.6 Isomerases altering macromolecular conformation (29 August 2018)
EC 5.6.1 Enzymes altering polypeptide conformation or assembly (29 August 2018)
EC 5.6.1.1 microtubule-severing ATPase (29 August 2018)
*EC 6.2.1.2 medium-chain acyl-CoA ligase (29 August 2018)
EC 6.2.1.53 L-proline—[L-prolyl-carrier protein] ligase (29 March 2018)
EC 6.2.1.54 D-alanine—[D-alanyl-carrier protein] ligase (29 March 2018)
EC 6.2.1.55 E1 SAMP-activating enzyme (21 May 2018)
EC 6.3.2.52 jasmonoyl—L-amino acid synthetase (20 February 2018)
*EC 6.3.4.14 biotin carboxylase (20 February 2018)
*EC 6.3.4.15 biotin—[biotin carboxyl-carrier protein] ligase (20 February 2018)
*EC 6.4.1.2 acetyl-CoA carboxylase (20 February 2018)
EC 7 Translocases (29 August 2018)
EC 7.1 Catalysing the translocation of hydrons (29 August 2018)
EC 7.1.1 Hydron translocation or charge separation linked to oxidoreductase reactions (29 August 2018)
EC 7.1.1.1 proton-translocating NAD(P)+ transhydrogenase (29 August 2018)
EC 7.1.1.2 NADH:ubiquinone reductase (H+-translocating) (29 August 2018)
EC 7.1.2 Hydron translocation linked to the hydrolysis of a nucleoside triphosphate (29 August 2018)
EC 7.1.2.1 H+-exporting ATPase (29 August 2018)
EC 7.1.2.2 H+-transporting two-sector ATPase (29 August 2018)
EC 7.1.3 Hydron translocation linked to the hydrolysis of diphosphate (29 August 2018)
EC 7.1.3.1 H+-exporting diphosphatase (29 August 2018)
EC 7.2 Catalysing the translocation of inorganic cations (29 August 2018)
EC 7.2.1 Linked to oxidoreductase reactions (29 August 2018)
EC 7.2.1.1 NADH:ubiquinone reductase (Na+-transporting) (29 August 2018)
EC 7.2.1.2 ferredoxin—NAD+ oxidoreductase (Na+-transporting) (29 August 2018)
EC 7.2.2 Linked to the hydrolysis of a nucleoside triphosphate (29 August 2018)
EC 7.2.2.1 Na+-transporting two-sector ATPase (29 August 2018)
EC 7.2.2.2 ABC-type Cd2+ transporter (29 August 2018)
EC 7.2.2.3 P-type Na+ transporter (29 August 2018)
EC 7.2.2.4 ABC-type Na+ transporter (29 August 2018)
EC 7.2.4 Linked to decarboxylation (29 August 2018)
EC 7.2.4.1 carboxybiotin decarboxylase (29 August 2018)
EC 7.2.4.2 oxaloacetate decarboxylase (Na+ extruding) (29 August 2018)
EC 7.2.4.3 (S)-methylmalonyl-CoA decarboxylase (sodium-transporting) (29 August 2018)
EC 7.3 Catalysing the translocation of inorganic anions and their chelates (29 August 2018)
EC 7.3.2 Linked to the hydrolysis of a nucleoside triphosphate (29 August 2018)
EC 7.3.2.1 ABC-type phosphate transporter (29 August 2018)
EC 7.3.2.2 ABC-type phosphonate transporter (29 August 2018)
EC 7.4 Catalysing the translocation of amino acids and peptides (29 August 2018)
EC 7.4.2 Linked to the hydrolysis of a nucleoside triphosphate (29 August 2018)
EC 7.4.2.1 ABC-type polar-amino-acid transporter (29 August 2018)
EC 7.4.2.2 ABC-type nonpolar-amino-acid transporter (29 August 2018)
EC 7.5 Catalysing the translocation of carbohydrates and their derivatives (29 August 2018)
EC 7.5.2 Linked to the hydrolysis of a nucleoside triphosphate (29 August 2018)
EC 7.5.2.1 ABC-type maltose transporter (29 August 2018)
EC 7.5.2.2 ABC-type oligosaccharide transporter (29 August 2018)
EC 7.6 Catalysing the translocation of other compounds (29 August 2018)
EC 7.6.2 Linked to the hydrolysis of a nucleoside triphosphate (29 August 2018)
EC 7.6.2.1 P-type phospholipid transporter (29 August 2018)
EC 7.6.2.2 ABC-type xenobiotic transporter (29 August 2018)
EC 7.6.2.3 ABC-type glutathione-S-conjugate transporter (29 August 2018)


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