New enzymes (February to April 2008, approved March to May 2008)An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry.
New enzymes (June to December 2008, approved July 2008 to January 2009)
Minor changes
EC 1.1.1.295 momilactone-A synthase (22 April 2008)
EC 1.1.1.296 dihydrocarveol dehydrogenase (21 June 2008)
EC 1.1.1.297 limonene-1,2-diol dehydrogenase (21 June 2008)
*EC 1.1.3.41 alditol oxidase (16 December 2008)
EC 1.1.99.32 L-sorbose 1-dehydrogenase (8 February 2008)
EC 1.2.1.73 sulfoacetaldehyde dehydrogenase (29 July 2008)
EC 1.3.1.81 (+)-pulegone reductase (29 July 2008)
EC 1.3.1.82 (–)-isopiperitenone reductase (17 September, 2008)
EC 1.3.7.6 phycoerythrobilin synthase (22 April 2008)
EC 1.3.99.24 2-amino-4-deoxychorismate dehydrogenase (22 April 2008)
EC 1.3.99.25 carvone reductase (21 June 2008)
*EC 1.4.3.4 monoamine oxidase (29 July 2008)
EC 1.4.3.6 deleted now EC 1.4.3.21 and EC 1.4.3.22 (29 July 2008)
*EC 1.4.3.16 L-aspartate oxidase (12 November 2008)
EC 1.4.3.21 primary-amine oxidase (29 July 2008)
EC 1.4.3.22 diamine oxidase (29 July 2008)
*EC 1.5.1.12 1-pyrroline-5-carboxylate dehydrogenase (8 February 2008)
EC 1.13.12.15 3,4-dihydroxyphenylalanine oxidative deaminase (12 November 2008)
EC 1.14.13.104 (+)-menthofuran synthase (29 July 2008)
EC 1.14.13.105 monocyclic monoterpene ketone monooxygenase (21 June 2008)
EC 1.14.13.106 epi-isozizaene 5-monooxygenase (16 December 2008)
EC 1.14.19.4 Δ8-fatty-acid desaturase (29 July 2008)
EC 1.14.19.5 Δ11-fatty-acid desaturase (13 September, 2008)
EC 1.14.19.6 Δ12-fatty-acid desaturase (13 September, 2008)
EC 1.14.21.7 biflaviolin synthase (16 December 2008)
*EC 2.1.1.70 8-hydroxyfuranocoumarin 8-O-methyltransferase (8 February 2008)
EC 2.1.1.93 deleted, identical to EC 2.1.1.70 (8 February 2008)
EC 2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase (25 November 2008)
EC 2.1.3.11 N-succinylornithine carbamoyltransferase (12 November 2008)
EC 2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (11 June 2008)
*EC 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase (25 November 2008)
*EC 2.3.1.94 6-deoxyerythronolide-B synthase (12 November 2008)
EC 2.3.1.185 tropine acyltransferase (22 April 2008)
EC 2.3.1.186 pseudotropine acyltransferase (22 April 2008)
EC 2.3.1.187 acetyl-S-ACP:malonate ACP transferase (25 November 2008)
*EC 2.4.1.14 sucrose-phosphate synthase (16 December 2008)
EC 2.4.1.245 α,α-trehalose synthase (29 July 2008)
EC 2.5.1.64 transferred to EC 2.2.1.9 and
EC 4.2.99.20
EC 2.5.1.72 quinolinate synthase (14 November 2008)
EC 2.6.1.86 2-amino-4-deoxychorismate synthase (22 April 2008)
EC 2.7.1.161 CTP-dependent riboflavin kinase (22 April 2008)
EC 2.7.1.162 N-acetylhexosamine 1-kinase (22 April 2008)
*EC 2.7.7.61 citrate lyase holo-[acyl-carrier protein] synthase (21 June 2008)
EC 2.7.7.65 diguanylate cyclase (8 February 2008)
EC 2.7.7.66 malonate decarboxylase holo-[acyl-carrier protein] synthase (21 June 2008)
*EC 2.7.8.25 triphosphoribosyl-dephospho-CoA synthase (21 June 2008)
EC 3.1.1.83 monoterpene ε-lactone hydrolase (21 June 2008)
*EC 3.1.3.24 sucrose-phosphate phosphatase (16 December 2008)
EC 3.1.3.78 phosphatidylinositol-4,5-bisphosphate 4-phosphatase (12 November 2008)
EC 3.1.4.52 cyclic-guanylate-specific phosphodiesterase (8 February 2008)
EC 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase (21 June 2008)
EC 3.1.7.4 sclareol cyclase (21 June 2008)
EC 3.1.26.12 ribonuclease E (29 July 2008)
*EC 3.2.1.97 glycopeptide α-N-acetylgalactosaminidase (16 December 2008)
EC 3.2.1.110 deleted identical to EC 3.2.1.97(16 December 2008)
EC 3.2.1.165 exo-1,4-β-D-glucosaminidase (22 April 2008)
EC 3.2.2.26 futalosine hydrolase (12 November 2008)
EC 3.4.11.24 aminopeptidase S (29 July 2008)
EC 3.4.22.68 Ulp1 peptidase (8 February 2008)
*EC 3.5.1.54 allophanate hydrolase (8 February 2008)
*EC 3.5.1.77 N-carbamoyl-D-amino-acid hydrolase (12 November 2008)
*EC 3.5.1.84 biuret amidohydrolase (8 February 2008)
*EC 3.5.1.87 N-carbamoyl-L-amino-acid hydrolase (12 November 2008)
EC 3.5.1.98 histone deacetylase (8 February 2008)
*EC 3.5.2.15 cyanuric acid amidohydrolase (8 February 2008)
EC 3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase (12 November 2008)
EC 4.1.1.87 malonyl-S-ACP decarboxylase (25 November 2008)
EC 4.1.1.88 biotin-independent malonate decarboxylase (25 November 2008)
EC 4.1.1.89 biotin-dependent malonate decarboxylase (25 November 2008)
EC 4.1.2.43 3-hexulose-6-phosphate synthase (12 November 2008)
*EC 4.2.1.92 hydroperoxide dehydratase (12 November 2008)
EC 4.2.3.28 ent-cassa-12,15-diene synthase (22 April 2008)
EC 4.2.3.29 ent-sandaracopimaradiene synthase (22 April 2008)
EC 4.2.3.30 ent-pimara-8(14),15-diene synthase (22 April 2008)
EC 4.2.3.31 ent-pimara-9(11),15-diene synthase (22 April 2008)
EC 4.2.3.32 levopimaradiene synthase (22 April 2008)
EC 4.2.3.33 stemar-13-ene synthase (22 April 2008)
EC 4.2.3.34 stemod-13(17)-ene synthase (22 April 2008)
EC 4.2.3.35 syn-pimara-7,15-diene synthase (22 April 2008)
EC 4.2.3.36 terpentetriene synthase (21 June 2008)
EC 4.2.3.37 epi-isozizaene synthase (16 December 2008)
EC 4.2.99.20 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (21 June 2008)
*EC 4.3.1.3 histidine ammonia-lyase (8 February 2008)
EC 4.3.1.5 transferred, now divided into EC 4.3.1.23, EC 4.3.1.24 and EC 4.3.1.25 (8 February 2008)
EC 4.3.1.23 tyrosine ammonia-lyase (8 February 2008)
EC 4.3.1.24 phenylalanine ammonia-lyase (8 February 2008)
EC 4.3.1.25 phenylalanine/tyrosine ammonia-lyase (8 February 2008)
EC 4.3.99.2 carboxybiotin decarboxylase (25 November 2008)
EC 5.1.99.5 hydantoin racemase (12 November 2008)
EC 5.3.1.27 6-phospho-3-hexuloisomerase (12 November 2008)
EC 5.5.1.14 syn-copalyl diphosphate synthase (22 April 2008)
EC 5.5.1.15 terpentedienyl-diphosphate synthase (21 June 2008)
EC 5.5.1.16 halimadienyl-diphosphate synthase (21 June 2008)
EC 6.2.1.35 ACP-SH:acetate ligase (25 November 2008)