IUBMB Enzyme Nomenclature

EC 7.2.2.15

Accepted name: P-type Ag+ transporter

Reaction: ATP + H2O + Ag+[side 1] = ADP + phosphate + Ag+[side 2]

Other name(s): Ag+-exporting ATPase

Systematic name: ATP phosphohydrolase (P-type, Ag+-exporting)

Comments: A P-type ATPase that exports Ag+ ions from some bacteria, archaea as well as from some animal tissues. The proteins also transport Cu+ ions (cf. EC 7.2.2.8, P-type Cu+ transporter).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Gupta, A., Matsui, K., Lo, J.F. and Silver, S. Molecular basis for resistance to silver cations in Salmonella. Nature Med. 5 (1999) 183-188. [PMID: 9930866]

2. Bury, N.R., Grosell, M., Grover, A.K. and Wood, C.M. ATP-dependent silver transport across the basolateral membrane of rainbow trout gills. Toxicol. Appl. Pharmacol. 159 (1999) 1-8. [PMID: 10448119]

[EC 7.2.2.15 created 2000 as EC 3.6.3.53, transferred 2018 to EC 7.2.2.15]


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