IUBMB Enzyme Nomenclature


Accepted name: biotin carboxylase

Reaction: ATP + biotin-carboxyl-carrier protein + HCO3 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein

Other name(s): biotin carboxylase (component of acetyl CoA carboxylase)

Systematic name: biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming)

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9075-71-2


1. Dimroth, P., Guchhait, R.B., Stoll, E. and Lane, M.D. Enzymatic carboxylation of biotin: molecular and catalytic properties of a component enzyme of acetyl CoA carboxylase. Proc. Natl. Acad. Sci. USA 67 (1970) 1353-1360. [PMID: 4922289]

[EC created 1976, modified 2014]

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