IUBMB Enzyme Nomenclature

EC 5.4.99.49

Accepted name: glutinol synthase

Reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = glutinol

For diagram of reaction click here.

Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, glutinol-forming)

Comments: The enzyme from Kalanchoe daigremontiana also gives traces of other triterpenoids.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Wang, Z., Yeats, T., Han, H. and Jetter, R. Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids. J. Biol. Chem. 285 (2010) 29703-29712. [PMID: 20610397]

[EC 5.4.99.49 created 2011]


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