IUBMB Enzyme Nomenclature

EC 5.4.99.3

Accepted name: 2-acetolactate mutase

Reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate

Other name(s): acetolactate mutase; acetohydroxy acid isomerase

Systematic name: 2-acetolactate methylmutase

Comments: Requires ascorbic acid; also converts 2-aceto-2-hydroxybutanoate to 3-hydroxy-3-methyl-2-oxopentanoate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37318-52-8

References:

1. Allaudeen, H.S. and Ramakrishnan, T. Biosynthesis of isoleucine and valine in Mycobacterium tuberculosis H37 Rv. Arch. Biochem. Biophys. 125 (1968) 199-209. [PMID: 4384955]

[EC 5.4.99.3 created 1972]


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