IUBMB Enzyme Nomenclature

EC 4.2.1.98

Accepted name: 16α-hydroxyprogesterone dehydratase

Reaction: 16α-hydroxyprogesterone = 16,17-didehydroprogesterone + H2O

For diagram click here.

Other name(s): hydroxyprogesterone dehydroxylase; 16α-hydroxyprogesterone dehydroxylase; 16α-dehydroxylase; 16α-hydroxyprogesterone hydro-lyase

Systematic name: 16α-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)

Comments: 16α-Hydroxypregnenolone is also a substrate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 89287-36-5

References:

1. Glass, T.L. and Lamppa, R.S. Purification and properties of 16α-hydroxyprogesterone dehydroxylase from Eubacterium sp. strain 144. Biochim. Biophys. Acta 837 (1985) 103-110. [PMID: 4052439]

[EC 4.2.1.98 created 1999, modified 2004 (EC 4.2.1.86 created 1989, incorporated 2004)]


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