IUBMB Enzyme Nomenclature


Accepted name: heme-transporting ATPase

Reaction: ATP + H2O + hemein = ADP + phosphate + hemeout

Systematic name: ATP phosphohydrolase (heme-exporting)

Comments: ABC-type (ATP-binding cassette-type) ATPase, characterised by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. An enzyme found in Gram-negative bacteria that exports heme.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Saier, M.H., Jr. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv. Microb. Physiol. 40 (1998) 81-136. [PMID: 9889977]

2. Jekabsons, W. and Schuster, W. orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria. Mol. Gen. Genet. 246 (1995) 166-173. [PMID: 7862087]

3. Ramseier, T.M., Winteler, H.V. and Hennecke, H. Discovery and sequence analysis of bacterial genes involved in the biogenesis of c-type cytochromes. J. Biol. Chem. 266 (1991) 7793-7803. [PMID: 1850420]

[EC created 2000]

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