IUBMB Enzyme Nomenclature

EC 3.6.3.39

Accepted name: lipopolysaccharide-transporting ATPase

Reaction: ATP + H2O + lipopolysaccharidein = ADP + phosphate + lipopolysaccharideout

Systematic name: ATP phosphohydrolase (lipopolysaccharide-exporting)

Comments: ABC-type (ATP-binding cassette-type) ATPase, characterised by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. Enzymes of Gram-negative bacteria that export lipo-oligosaccharides and lipopolysaccharides.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Fath, M.J. and Kolter, R. ABC transporters: bacterial exporters. Microbiol. Rev. 57 (1993) 995-1017. [PMID: 8302219]

2. Fernandez-Lopez, M., D'Haeze, W., Mergaert, P., Verplancke, C., Prome, J.C., Van Montagu, M. and Holstens, M. Role of nod1and nodJ in lipo-chitooligosaccharide secretion in Azorhizobium caulinodans and Escherichia coli. Mol. Microbiol. 20 (1996) 993-1000. [PMID: 8809752]

3. Paulsen, I.T., Beness, A.M. and Saier, M.H., Jr. Computer-based analysis of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria. Microbiology 143 (1997) 2685-2699. [PMID: 9274022]

4. Saier, M.H., Jr. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv. Microb. Physiol. 40 (1998) 81-136. [PMID: 9889977]

[EC 3.6.3.39 created 2000]


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