IUBMB Enzyme Nomenclature

EC 3.5.5.4

Accepted name: cyanoalanine nitrilase

Reaction: 3-cyano-L-alanine + 2 H2O = L-aspartate + NH3 (overall reaction)
(1a) 3-cyano-L-alanine + H2O = L-asparagine
(1b) L-asparagine + H2O = L-aspartate + NH3

Other name(s): β-cyanoalanine nitrilase

Systematic name: 3-cyano-L-alanine aminohydrolase

Comments: L-Asparagine is formed as an intermediate. cf. EC 4.2.1.65, 3-cyanoalanine hydratase and EC 3.5.1.1, asparaginase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 85638-44-4

References:

1. Yanase, H., Sakai, T. and Tonomuro, K. Purification, crystallization and some properties of β-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13. Agric. Biol. Chem. 47 (1983) 473-482.

[EC 3.5.5.4 created 1986]


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