Reaction: 2,5-dioxopiperazine + H2O = glycylglycine
Other name(s): cyclo(Gly-Gly) hydrolase; cyclo(glycylglycine) hydrolase
Systematic name: 2,5-dioxopiperazine amidohydrolase
Comments: Highly specific; does not hydrolyse other dioxopiperazines, glycylglycine, proteins or barbiturates.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 97599-45-6
References:
1. Suzuki, Y. and Uchida, K. Multiple forms of α-glycosidase from pig duodenum. Agric. Biol. Chem. 49 (1985) 1573-1581.