IUBMB Enzyme Nomenclature

EC 3.4.23.2

Accepted name: pepsin B

Reaction: Degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than that of pepsin A; does not cleave at Phe1-Val, Gln4-His or Gly23-Phe

Other names: parapepsin I; pig gelatinase

Comments: Formed from pig pepsinogen B. In peptidase family A1 (pepsin A family)

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: 9025-48-3

References:

1. Ryle, A.P. The porcine pepsins and pepsinogens. Methods Enzymol. 19 (1970) 316-336

[EC 3.4.23.2 created 1961 as EC 3.4.4.2, transferred 1972 to EC 3.4.23.2, modified 1986]


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