Reaction: Endonucleolytic cleavage to 5'-phosphomononucleotide and 5'-phosphooligonucleotide end-products
Other name(s): endonuclease (Serratia marcescens); barley nuclease; plant nuclease I; nucleate endonuclease
Comments: Hydrolyses double- or single-stranded substrate. Formerly EC 3.1.4.9.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9025-65-4
References:
1. Mikulski, A.J. and Laskowski, M., Sr. Mung bean nuclease I. 3. Purification procedure and (3') omega monophosphatase activity. J. Biol. Chem. 245 (1970) 5026-5031. [PMID: 4319109]
2. Stevens, A. and Hilmoe, R.J. Studies on a nuclease from Azotobacter agilis. I. Isolation and mode of action. J. Biol. Chem. 235 (1960) 3016-3022.
3. Stevens, A. and Hilmoe, R.J. Studies on a nuclease from Azotobacter agilis. II. Hydrolysis of ribonucleic and deoxyribonucleic acids. J. Biol. Chem. 235 (1960) 3023-3027.
4. Wechter, W.J., Mikulski, A.J. and Laskowski, M., Sr. Gradation of specificity with regard to sugar among nucleases. Biochem. Biophys. Res. Commun. 30 (1968) 318-322. [PMID: 4296679]