IUBMB Enzyme Nomenclature

EC 3.1.1.61

Accepted name: protein-glutamate methylesterase

Reaction: protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol

Other name(s): chemotaxis-specific methylesterase; methyl-accepting chemotaxis protein methyl-esterase; CheB methylesterase; methylesterase CheB; protein methyl-esterase; protein carboxyl methylesterase; PME; protein methylesterase

Systematic name: protein-L-glutamate-O5-methyl-ester acylhydrolase

Comments: Hydrolyses the products of EC 2.1.1.77 (protein-L-isoaspartate(D-aspartate) O-methyltransferase), EC 2.1.1.78 (isoorientin 3'-O-methyltransferase), EC 2.1.1.80 (protein-glutamate O-methyltransferase) and EC 2.1.1.100 (protein-S-isoprenylcysteine O-methyltransferase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 69552-31-4

References:

1. Gagnon, C., Harbour, G. and Camato, R. Purification and characterization of protein methylesterase from rat kidney. J. Biol. Chem. 259 (1984) 10212-10215. [PMID: 6469959]

2. Kehry, M.R., Doak, T.G. and Dahlquist, F.W. Stimulus-induced changes in methylesterase activity during chemotaxis in Escherichia coli. J. Biol. Chem. 259 (1984) 11828-11835. [PMID: 6384215]

[EC 3.1.1.61 created 1989, modified 2002]


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