Reaction: 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate
For diagram click here.
Glossary: 3'-phosphoadenylyl sulfate = PAPS
Other names: chondroitin 6-O-sulfotransferase; 3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase; terminal 6-sulfotransferase; 3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase
Systematic name: 3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfonotransferase
Comments: The sulfation is at the 6-position of N-acetylgalactosamine residues of chondroitin. Not identical with EC 2.8.2.5 chondroitin 4-sulfotransferase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37292-93-6
References:
1. Habuchi, O. and Miyashita, N. Separation and characterization of chondroitin 6-sulfotransferase and chondroitin 4-sulfotransferase from chick embryo cartilage. Biochim. Biophys. Acta 717 (1982) 414-421. [PMID: 6957247]