Reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin
Other name(s): tropomyosin kinase (phosphorylating); STK (ambiguous)
Systematic name: ATP:tropomyosin O-phosphotransferase
Comments: The enzyme phosphorylates casein equally well, and histone and phosvitin to a lesser extent. The acceptor is a serine residue in the protein.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 90804-56-1
References:
1. deBelle, I. and Mak, A.S. Isolation and characterization of tropomyosin kinase from chicken embryo. Biochim. Biophys. Acta 925 (1987) 17-26. [PMID: 3593768]
2. Montgomery, K. and Mak, A.S. In vitro phosphorylation of tropomyosin by a kinase from chicken embryo. J. Biol. Chem. 259 (1984) 5555-5560. [PMID: 6325440]
3. Watson, M.H., Taneja, A.K., Hodges, R.S. and Mak, A.S. Phosphorylation of αα- and ββ-tropomyosin and synthetic peptide analogues. Biochemistry 27 (1988) 4506-4512. [PMID: 3166994]