IUBMB Enzyme Nomenclature

EC 2.5.1.34

Accepted name: 4-dimethylallyltryptophan synthase

Reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan

For diagram of reaction click here.

Other name(s): dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase; dimethylallyltryptophan synthetase; dimethylallylpyrophosphate:tryptophan dimethylallyl transferase; DMAT synthetase; 4-(γ,γ-dimethylallyl)tryptophan synthase; tryptophan dimethylallyltransferase

Systematic name: dimethylallyl-diphosphate:L-tryptophan 4-dimethylallyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 55127-01-0

References:

1. Lee, S.L., Floss, H.G. and Heinstein, P. Purification and properties of dimethylallylpyrophosphate:tryptophan dimethylallyl transferase, the first enzyme of ergot alkaloid biosynthesis in Claviceps sp. SD 58. Arch. Biochem. Biophys. 177 (1976) 84-94. [PMID: 999297]

[EC 2.5.1.34 created 1984, modified 2010]


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