IUBMB Enzyme Nomenclature

EC 2.5.1.27

Accepted name: adenylate dimethylallyltransferase

Reaction: prenyl diphosphate + AMP = diphosphate + N6-prenyladenosine 5′-phosphate

For diagram of reaction, click here

Other name(s): cytokinin synthase (ambiguous); isopentenyltransferase (ambiguous); 2-isopentenyl-diphosphate:AMP Δ2-isopentenyltransferase; adenylate isopentenyltransferase (ambiguous); IPT; adenylate dimethylallyltransferase; dimethylallyl-diphosphate:AMP dimethylallyltransferase

Systematic name: prenylyl-diphosphate:AMP prenyltransferase

Comments: Involved in the biosynthesis of cytokinins in plants. Some isoforms from the plant Arabidopsis thaliana are specific for AMP while others also have the activity of EC 2.5.1.112, adenylate dimethylallyltransferase (ADP/ATP-dependent).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 72840-95-0

References:

1. Chen, C.-M. and Melitz, D.K. Cytokinin biosynthesis in a cell-free system from cytokinin-autotrophic tobacco tissue cultures. FEBS Lett. 107 (1979) 15-20. [PMID: 499537]

2. Takei, K., Sakakibara, H. and Sugiyama, T. Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana. J. Biol. Chem. 276 (2001) 26405-26410. [PMID: 11313355]

3. Sakano, Y., Okada, Y., Matsunaga, A., Suwama, T., Kaneko, T., Ito, K., Noguchi, H. and Abe, I. Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.). Phytochemistry 65 (2004) 2439-2446. [PMID: 15381407]

[EC 2.5.1.27 created 1984, modified 2002, modified 2013]


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