IUBMB Enzyme Nomenclature

EC 2.4.1.56

Accepted name: lipopolysaccharide N-acetylglucosaminyltransferase

Reaction: UDP-N-acetyl-α-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyllipopolysaccharide

Other name(s): UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase

Systematic name: UDP-N-acetyl-α-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase

Comments: Transfers N-acetylglucosaminyl residues to a D-galactose residue in the partially completed lipopolysaccharide core [cf. EC 2.4.1.44 (lipopolysaccharide 3-α-galactosyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37277-64-8

References:

1. Osborn, M.J. and D'Ari, L. Enzymatic incorporation of N-acetylglucosamine into cell wall lipopolysaccharide in a mutant strain of Salmonella typhimurium. Biochem. Biophys. Res. Commun. 16 (1964) 568-575.

[EC 2.4.1.56 created 1972]


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