IUBMB Enzyme Nomenclature

EC 2.4.1.353

Accepted name: sordaricin 6-deoxyaltrosyltransferase

Reaction: GDP-6-deoxy-α-D-altrose + sordaricin = 4'-O-demethylsordarin + GDP

For diagram of reaction click here.

Glossary: sordaricin = (1R,3aR,4S,4aR,7R,7aR,8aR)-4-formyl-8a-(hydroxymethyl)-7-methyl-3-(propan-2-yl)-1,3a,4,4a,5,6,7,7a,8,8-decahydro-1,4-methanocyclopenta[f]indene-3a-carboxylic acid

Other name(s): SdnJ

Systematic name: GDP-6-deoxy-α-D-altrose:sordaricin 6-deoxy-D-altrosyltransferase

Comments: The enzyme, isolated from the fungus Sordaria araneosa, is involved in the biosynthesis of the glycoside antibiotic sordarin.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Kudo, F., Matsuura, Y., Hayashi, T., Fukushima, M. and Eguchi, T. Genome mining of the sordarin biosynthetic gene cluster from Sordaria araneosa Cain ATCC 36386: characterization of cycloaraneosene synthase and GDP-6-deoxyaltrose transferase. J. Antibiot. (Tokyo) 69 (2016) 541-548. [PMID: 27072286]

[EC 2.4.1.353 created 2018]


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