Reaction: acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate
Other name(s): chloramphenicol acetyltransferase; chloramphenicol acetylase; chloramphenicol transacetylase; CAT I; CAT II; CAT III
Systematic name: acetyl-CoA:chloramphenicol 3-O-acetyltransferase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9040-07-7
References:
1. Shaw, W.V. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli. J. Biol. Chem. 242 (1967) 687-693. [PMID: 5335032]
2. Shaw, W.V. and Brodsky, R.F. Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus. J. Bacteriol. 95 (1968) 28-36. [PMID: 4965980]