Reaction: an acyl-CoA + sphingosine = CoA + an N-acylsphingosine
Other name(s): ceramide synthetase; sphingosine acyltransferase
Systematic name: acyl-CoA:sphingosine N-acyltransferase
Comments: Acts on sphingosine or its 2-epimer.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37257-09-3
References:
1. Sribney, M. Enzymatic synthesis of ceramide. Biochim. Biophys. Acta 125 (1966) 542-547. [PMID: 5973195]