Reaction: carbamoyl phosphate + a 3-hydroxymethylceph-3-em-4-carboxylate = phosphate + a 3-carbamoyloxymethylcephem
Systematic name: carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase
Comments: Acts on a wide range of 3-hydroxymethylcephems (a subclass of the cephalosporin antibiotics). Activated by ATP.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 74315-96-1
References:
1. Brewer, S.J., Taylor, P.M. and Turner, M.K. An adenosine triphosphate-dependent carbamoylphosphate--3-hydroxymethylcephem O-carbamoyltransferase from Streptomyces clavuligerus. Biochem. J. 185 (1980) 555-564.