EC 2.1.1.223

Reaction: S-adenosyl-L-methionine + adenine³⁷ in tRNA₁^Val = S-adenosyl-L-homocysteine + N⁶-methyladenine³⁷ in tRNA₁^Val

Other name(s): YfiC

Systematic name: S-adenosyl-L-methionine:tRNA₁^Val (adenine³⁷-N⁶)-methyltransferase

Comments: The enzyme specifically methylates adenine³⁷ in tRNA₁^Val (anticodon cmo5UAC).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Golovina, A.Y., Sergiev, P.V., Golovin, A.V., Serebryakova, M.V., Demina, I., Govorun, V.M. and Dontsova, O.A. The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA₁^Val(cmo⁵UAC). RNA 15 (2009) 1134-1141. [PMID: 19383770]