Reaction: S-adenosyl-L-methionine + palmatine + 2 NADPH + H+ = S-adenosyl-L-homocysteine + corydaline + 2 NADP+
For diagram click here.
Systematic name: S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase
Comments: Also acts on 7,8-dihydropalmatine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 155807-67-3
References:
1. Rueffer, M., Bauer, W. and Zenk, M.H. The formation of corydaline and related alkaloids in Corydalis cava in vivo and in vitro. Canad. J. Chem. 72 (1994) 170-175.