IUBMB Enzyme Nomenclature

EC 1.6.5.11

Accepted name: NADH dehydrogenase (quinone)

Reaction: NADH + H+ + a quinone = NAD+ + a quinol

Other name(s): reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase; NADH-quinone oxidoreductase; DPNH-menadione reductase; D-diaphorase; NADH2 dehydrogenase (quinone)

Systematic name: NADH:(quinone-acceptor) oxidoreductase

Comments: Menaquinone can act as acceptor. Inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Koli, A.K., Yearby, C., Scott, W. and Donaldson, K.O. Purification and properties of three separate menadione reductases from hog liver. J. Biol. Chem. 244 (1969) 621-629. [PMID: 4388793]

[EC 1.6.5.11 created 1972 as EC 1.6.99.5, transferred 2015 to EC 1.6.5.11]


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