IUBMB Enzyme Nomenclature

EC 1.4.3.25

Accepted name: L-arginine oxidase

Reaction: L-arginine + H2O + O2 = 5-guanidino-2-oxopentanoate + NH3 + H2O2

Systematic name: L-arginine:oxygen oxidoreductase (deaminating)

Comments: Contains FAD. The enzyme from cyanobacteria can also act on other basic amino acids with lower activity. The enzyme from the bacterium Pseudomonas sp. TPU 7192 is highly specific.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Miller, D.L. and Rodwell, V.W. Metabolism of basic amino acids in Pseudomonas putida. Intermediates in L-arginine catabolism. J. Biol. Chem. 246 (1971) 5053-5058. [PMID: 5570437]

2. Pistorius, E.K. and Voss, H. Some properties of a basic L-amino-acid oxidase from Anacystis nidulans. Biochim. Biophys. Acta 611 (1980) 227-240. [PMID: 6766743]

3. Gau, A.E., Heindl, A., Nodop, A., Kahmann, U. and Pistorius, E.K. L-amino acid oxidases with specificity for basic L-amino acids in cyanobacteria. Z. Naturforsch. C 62 (2007) 273-284. [PMID: 17542496]

4. Matsui, D., Terai, A. and Asano, Y. L-Arginine oxidase from Pseudomonas sp. TPU 7192: Characterization, gene cloning, heterologous expression, and application to L-arginine determination. Enzyme Microb. Technol. 82 (2016) 151-157. [PMID: 26672462]

[EC 1.4.3.25 created 2017]


Return to EC 1.4.3 home page
Return to EC 1.4 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page