Reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor
Other name(s): branched-chain acyl-CoA dehydrogenase; 2-methyl branched chain acyl-CoA dehydrogenase; 2-methylbutanoyl-CoA:(acceptor) oxidoreductase
Systematic name: 2-methylbutanoyl-CoA:acceptor oxidoreductase
Comments: Also oxidizes 2-methylpropanoyl-CoA. Not identical with EC 22.214.171.124 (butyryl-CoA dehydrogenase), EC 126.96.36.199 (medium-chain acyl-CoA dehydrogenase), EC 188.8.131.52 (long-chain acyl-CoA dehydrogenase), EC 184.108.40.206 (very-long-chain acyl-CoA dehydrogenase) or EC 220.127.116.11 (isovaleryl-CoA dehydrogenase).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 85130-32-1
1. Ikeda, Y., Dabrowski, C. and Tanaka, K. Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase. J. Biol. Chem. 258 (1983) 1066-1076. [PMID: 6401712]