IUBMB Enzyme Nomenclature

EC 1.21.3.5

Accepted name: sulochrin oxidase [(–)-bisdechlorogeodin-forming]

Reaction: 2 sulochrin + O2 = 2 (–)-bisdechlorogeodin + 2 H2O

For diagram click here.

Other name(s): sulochrin oxidase

Systematic name: sulochrin:oxygen oxidoreductase (cyclizing, (–)-specific)

Comments: Also acts on several diphenols and phenylenediamines, but has low affinity for these substrates. Involved in the biosynthesis of mould metabolites related to the antibiotic griseofulvin.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 82469-87-2

References:

1. Nordlöv, H. and Gatenbeck, S. Enzymatic synthesis of (+)- and (–)-bisdechlorogeodin with sulochrin oxidase from Penicillium frequentans and Oospora sulphurea ochracea. Arch. Microbiol. 131 (1982) 208-211. [PMID: 7049104]

[EC 1.21.3.5 created 1986 as EC 1.10.3.8, transferred 2002 to EC 1.21.3.5]


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