IUBMB Enzyme Nomenclature

EC 1.2.99.6

Accepted name: carboxylate reductase

Reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor

Other name(s): aldehyde:(acceptor) oxidoreductase

Systematic name: aldehyde:acceptor oxidoreductase

Comments: A tungsten protein. Methyl viologen can act as acceptor. In the reverse direction, non-activated acids are reduced by reduced viologens to aldehydes, but not to the corresponding alcohols.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 125008-36-8

References:

1. White, H., Strobl, G., Feicht, R. and Simon, H. Carboxylic acid reductase: a new tungsten enzyme catalyses the reduction of non-activated carboxylic acids to aldehydes. Eur. J. Biochem. 184 (1989) 89-96. [PMID: 2550230]

[EC 1.2.99.6 created 1992]


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