IUBMB Enzyme Nomenclature

EC 1.2.1.63

Accepted name: 6-oxohexanoate dehydrogenase

Reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + 2 H+

Systematic name: 6-oxohexanoate:NADP+ oxidoreductase

Comments: Last step in the cyclohexanol degradation pathway in Acinetobacter sp.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 62628-29-9

References:

1. Davey, J.F. and Trudgill, P.W. The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species. Eur. J. Biochem. 74 (1977) 115-127. [PMID: 856571]

2. Donoghue, N.A. and Trudgill P.W. The metabolism of cyclohexanol by Acinetobacter NCIB 9871. Eur. J. Biochem. 60 (1975) 1-7. [PMID: 1261]

[EC 1.2.1.63 created 2000]


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