IUBMB Enzyme Nomenclature

EC 1.2.1.53

Accepted name: 4-hydroxyphenylacetaldehyde dehydrogenase

Reaction: 4-hydroxyphenylacetaldehyde + NAD+ + H2O = 4-hydroxyphenylacetate + NADH + 2 H+

Other name(s): 4-HPAL dehydrogenase

Systematic name: 4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase

Comments: With EC 4.2.1.87 octopamine dehydratase, brings about the metabolism of octopamine in Pseudomonas.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 109456-56-6

References:

1. Cuskey, S.M., Peccoraro, V. and Olsen, R.H. Initial catabolism of aromatic biogenic amines by Pseudomonas aeruginosa PAO: pathway description, mapping of mutations, and cloning of essential genes. J. Bacteriol. 169 (1987) 2398-2404. [PMID: 3034855]

[EC 1.2.1.53 created 1989]


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