Reaction: lupanine + 2 ferricytochrome c + H2O = 17-hydroxylupanine + 2 ferrocytochrome c + 2 H+
Other name(s): lupanine dehydrogenase (cytochrome c)
Systematic name: lupanine:cytochrome c-oxidoreductase (17-hydroxylating)
Comments: The enzyme isolated from Pseudomonas putida contains heme c and requires pyrroloquinoline quinone (PQQ) for activity
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
References:
1. Hopper, D.J., Rogozinski, J. and Toczko, M. Lupanine hydroxylase, a quinocytochrome c from an alkaloid-degrading Pseudomonas sp. Biochem. J. 279 (1991) 105-109. [PMID: 1656935]
2. Hopper, D.J. and Kaderbhai, M.A. The quinohaemoprotein lupanine hydroxylase from Pseudomonas putida. Biochim. Biophys. Acta 1647 (2003) 110-115. [PMID: 12686118]