IUBMB Enzyme Nomenclature

EC 1.16.1.4

Accepted name: cob(II)alamin reductase

Reaction: 2 cob(I)alamin + NAD+ = 2 cob(II)alamin + NADH + H+

Other name(s): vitamin B12r reductase; B12r reductase; NADH2:cob(II)alamin oxidoreductase

Systematic name: cob(I)alamin:NAD+ oxidoreductase

Comments: A flavoprotein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37256-40-9

References:

1. Walker, G.A., Murphy, S. and Huennekens, F.M. Enzymatic conversion of vitamin B12a to adenosyl-B12: evidence for the existence of two separate reducing systems. Arch. Biochem. Biophys. 134 (1969) 95-102. [PMID: 4390543]

[EC 1.16.1.4 created 1972 as EC 1.6.99.9, transferred 2002 to EC 1.16.1.4]


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