IUBMB Enzyme Nomenclature

EC 1.16.1.1

Accepted name: mercury(II) reductase

Reaction: Hg + NADP+ + H+ = Hg2+ + NADPH

Other name(s): mercuric reductase; mercurate(II) reductase; mercuric ion reductase; mercury reductase; reduced NADP:mercuric ion oxidoreductase; mer A

Systematic name: Hg:NADP+ oxidoreductase

Comments: A dithiol enzyme.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, UM-BBD, CAS registry number: 67880-93-7

References:

1. Fox, B.S. and Walsh, C.T. Mercuric reductase. Purification and characterization of a transposon-encoded flavoprotein containing an oxidation-reduction-active disulfide. J. Biol. Chem. 257 (1982) 2498-2503. [PMID: 6277900]

2. Fox, B.S. and Walsh, C.T. Mercuric reductase - homology to glutathione-reductase and lipoamide dehydrogenase - iodoacetamide alkylation and sequence of the active-site peptide. Biochemistry 22 (1983) 4082-4088.

[EC 1.16.1.1 created 1984]


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