Reaction: vinorine + NADPH + H+ + O2 = vomilenine + NADP+ + H2O
For diagram click here.
Systematic name: vinorine,NADPH:oxygen oxidoreductase (21α-hydroxylating)
Comments: A heme-thiolate protein (P-450). Forms a stage in the biosynthesis of the indole alkaloid ajmaline.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 162875-03-8
1. Falkenhagen, H. and Stöckligt, J. Enzymatic biosynthesis of vomilenine, a key intermediate of the ajmaline pathway, catalysed by a novel cytochrome P-450-dependent enzyme from plant cell cultures of Rauwolfia serpentina. Z. Naturforsch. C: Biosci. 50 (1995) 45-53.