IUBMB Enzyme Nomenclature


Accepted name: dihydrochelirubine 12-monooxygenase

Reaction:dihydrochelirubine + NADPH + H+ + O2 = 12-hydroxydihydrochelirubine + NADP+ + H2O

For diagram click here.

Other name(s): dihydrochelirubine 12-hydroxylase

Systematic name: dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)

Comments: a heme-thiolate protein (P-450)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 158736-41-5


1. Kammerer, L., De-Eknamkul, W. and Zenk, M.H. Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum. Phytochemistry 36 (1994) 1409-1416.

[EC created 1999]

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