Reaction: (S)-N-methylcanadine + NADPH + H+ + O2 = allocryptopine + NADP+ + H2O
For diagram click here.
Other name(s): methyltetrahydroprotoberberine 14-hydroxylase; (S)-cis-N-methyltetrahydroberberine 14-monooxygenase; (S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase
Systematic name: (S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating)
Comments: A heme-thiolate protein (P-450).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 113478-42-5
1. Rueffer, M. and Zenk, M.H. Enzymatic formation of protopines by a microsomal cytochrome-P-450 system of Corydalis vaginans. Tetrahedron Lett. 28 (1987) 5307-5310.