IUBMB Enzyme Nomenclature

EC 1.14.13.27

Accepted name: 4-aminobenzoate 1-monooxygenase

Reaction: 4-aminobenzoate + NAD(P)H + 2 H+ + O2 = 4-hydroxyaniline + NAD(P)+ + H2O + CO2

Other name(s): 4-aminobenzoate hydroxylase; 4-aminobenzoate monooxygenase

Systematic name: 4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)

Comments: A flavoprotein (FAD). Acts on anthranilate and 4-aminosalicylate but not on salicylate (cf. EC 1.14.13.1 salicylate 1-monooxygenase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 98668-55-4

References:

1. Tsuji, H., Ogawa, T., Bando, N. and Sasaoka, K. Purification and properties of 4-aminobenzoate hydroxylase, a new monooxygenase from Agaricus bisporus. J. Biol. Chem. 261 (1986) 13203-13209. [PMID: 3489713]

[EC 1.14.13.27 created 1989]


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