Reaction: resorcinol + NADPH + H+ + O2 = hydroxyquinol + NADP+ + H2O
Glossary: resorcinol = 1,3-dihydroxybenzene
hydroxyquinol = 1,2,4-trihydroxybenzene
Systematic name: resorcinol,NADPH:oxygen oxidoreductase (4-hydroxylating)
Comments: The enzyme, characterized from the bacterium Corynebacterium glutamicum, is a single-component hydroxylase. The enzyme has no activity with NADH. cf. EC 22.214.171.124, resorcinol 4-hydroxylase (NADH), and EC 126.96.36.199, resorcinol 4-hydroxylase (FADH2).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
1. Huang, Y., Zhao, K.X., Shen, X.H., Chaudhry, M.T., Jiang, C.Y. and Liu, S.J. Genetic characterization of the resorcinol catabolic pathway in Corynebacterium glutamicum. Appl. Environ. Microbiol. 72 (2006) 7238-7245. [PMID: 16963551]