IUBMB Enzyme Nomenclature


Accepted name: ent-isokaurene C2-hydroxylase

Reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2α-hydroxyisokaurene + H2O + NADP+

For diagram of reaction click here.

Other name(s): CYP71Z6

Systematic name: ent-isokaurene,NADPH:oxygen oxidoreductase (hydroxylating)

Comments: This is the initial step in the conversion of ent-isokaurene to the antibacterial oryzalides in rice, Oryza sativa.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Wu, Y., Hillwig, M.L., Wang, Q. and Peters, R.J. Parsing a multifunctional biosynthetic gene cluster from rice: biochemical characterization of CYP71Z6 & 7. FEBS Lett. 585 (2011) 3446-3451. [PMID: 21985968]

[EC created 2012]

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