IUBMB Enzyme Nomenclature


Accepted name: benzoate 4-monooxygenase

Reaction: benzoate + NADPH + H+ + O2 = 4-hydroxybenzoate + NADP+ + H2O

For diagram click here.

Other name(s): benzoic acid 4-hydroxylase; benzoate 4-hydroxylase; benzoic 4-hydroxylase; benzoate-p-hydroxylase; p-hydroxybenzoate hydroxylase

Systematic name: benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)

Comments: Requires Fe2+ and tetrahydropteridine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 39391-25-8


1. Reddy, C.C. and Vaidyanathan, C.S. Purification, properties and induction of a specific benzoate-4-hydroxylase from Aspergillus niger (UBC 814). Biochim. Biophys. Acta 384 (1975) 46-57. [PMID: 236777]

[EC created 1976]

Return to EC 1.14.13 home page
Return to EC 1.14 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page