IUBMB Enzyme Nomenclature

EC 1.13.12.2

Accepted name: lysine 2-monooxygenase

Reaction: L-lysine + O2 = 5-aminopentanamide + CO2 + H2O

Other name(s): lysine oxygenase; lysine monooxygenase; L-lysine-2-monooxygenase

Systematic name: L-lysine:oxygen 2-oxidoreductase (decarboxylating)

Comments: A flavoprotein (FAD). Also acts on other diamino acids.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9031-22-5

References:

1. Nakazawa, T., Hori, K. and Hayaishi, O. Studies on monooxygenases. V. Manifestation of amino acid oxidase activity by L-lysine monooxygenase. J. Biol. Chem. 247 (1972) 3439-3444. [PMID: 4624115]

2. Takeda, H. and Hayaishi, O. Crystalline L-lysine oxygenase. J. Biol. Chem. 241 (1966) 2733-2736. [PMID: 5911646]

3. Takeda, H., Yamamoto, S., Kojima, Y. and Hayaishi, O. Studies on monooxygenases. I. General properties of crystalline L-lysine monooxygenase. J. Biol. Chem. 244 (1969) 2935-2941. [PMID: 5772467]

[EC 1.13.12.2 created 1972]


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